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Titanium Complex with New Schiff Base 4-(N, N-dimethylaminobenzylidene)-1- phenylsemicarbazide: Synthesis, Thermal, XRD, and Antibacterial properties

4-(N, N-dimethylaminobenzylidene) 1-phenylsemicarbazide Schiff base (SB) was synthesized from 1-phenylsemicarbazide and 4-(N,N-dimethylaminobenzaldehyde). Numerous analytical approaches, such as ele-mental analysis, 1HNMR, 13CNMR, electronic spectra, and FT-IR spectroscopy were utilized to analyze the newly synthesized Schiff base. The Ti (IV) Schiff base complex was produced, and its electrolytic nature, stability, and octahedral structural properties were determined by elemental, IR, UV-Vis spectral, conductivity, and thermal studies (TGA-DTA). From XRD results, the practical size of Schiff base and its complex were in the nano range with crystallinity structure. To evaluate the antibacterial activity, the free ligand and its complex were assessed in vitro against Pseudomonas aeruginosa, Escherichia coli, and Staphylococcus aureus. These results show that the metal complex has stronger antibacterial action than the Schiff base ligand.

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Fathi M. Al-Azab
Department of Chemistry, Faculty of Science, Sana’a University, Sana’a, Yemen
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Yasmin M. S Jamil
Sana'a University
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Nedhal A. A. Al-Selwi
Department of Chemistry, Faculty of Science, Sana’a University, Sana’a, Yemen
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Ahmed N. Alhakimi
Department of Chemistry, Faculty of Science, Ibb University, Ibb, Yemen
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Dheya A. Hameed
Department of Chemistry, Faculty of Science, Sana’a University, Sana’a, Yemen
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Gamil M. S. Qasem
Department of Chemistry, Faculty of Science, Sana’a University, Sana’a, Yemen
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Abuzar Ebead Albadri Albadri
Department of Chemistry, Faculty of Science, Qassim University, Buraidah 51452, Saudi Arabia
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Titanium Complex with New Schiff Base 4-(N, N-dimethylaminobenzylidene)-1- phenylsemicarbazide: Synthesis, Thermal, XRD, and Antibacterial properties. (2024). Sana’a University Journal of Applied Sciences and Technology, 2(4), 391-402. https://doi.org/10.59628/jast.v2i4.1145

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