Antioxidant and antimicrobial of three extracts of Caralluma deflersiana Laver

Abstract

 This study focused on one traditional herb used in Yemen, Caralluma deflersiana. The antioxidant activity of the extracts was examined using the bipyridine-ferric reducing antioxidant capacity assay, as well as the antibacterial activity against S. aureus, P. aeruginosa, E. coli, and C. albicans microbial strains using the agar diffusion method. The highest antioxidant activity was observed for the ethyl acetate extract. 370 µg ASA/mg ascorbic equivalent µg ASA/mg (p< 0.05). Acetone and chloroform extracts showed decreased activity and 340 and 305 ascorbic equivalents µg ASA/mg, respectively. The three extracts inhibited the growth of the three bacterial and one fungal species, with MIC values ranging from 55.0- 80.7 µg/ml. The selected extracts may be developed to explore new pharmacological possibilities for their application.