Consanguinity is Strongly Associated with Fetal Congenital Anencephaly

Main Article Content

Alia A Shuaib

Abstract

Background: Anencephaly is a type of neural tube defect characterized by abnormal development of the brain and the bones of the skull. Aims: to investigate the association between consanguinity and anencephaly which is the most severe form of neural tube defects and to assess the magnitude of the problem. Methods :A case-control study was conducted between January and December 2014, all women with anencephaly that were admitted to the obstetric department of al Thawra General hospital , Sana'a , were enrolled in this study .The subjects were divided into study ( n = 72 ) and control groups (n=25).  Results: From a total of 11283 deliveries, 97 women were having anencephaly giving the overall incidence as 8.5/1000 births. We found significant number   (74.2%) of these affected women had consanguineous marriage (95% CI 62.5-83.7; p = 0.0001). The first cousin union was present in (68%). Compared with control, the study cases were characterized by poverty, low education, absence of antenatal care, and mostly from rural setting. Conclusion: Consanguineous marriage is common in our societies and strongly associated with fetal congenital anomalies particularly anencephaly.

Downloads

Download data is not yet available.

Article Details

How to Cite
Shuaib, A. A. (2023). Consanguinity is Strongly Associated with Fetal Congenital Anencephaly . Sana’a University Journal of Medicine and Health Sciences, 2(1). https://doi.org/10.59628/jchm.v2i1.303
Section
Article

Similar Articles

You may also start an advanced similarity search for this article.