Prevalence and Antibiogram Susceptibility of <em>Pseudomonas aeruginosa</em> among Burn Wound Patients in Sana’a city –Yemen
Background and aim: Burn injuries are prevalent globally, and Pseudomonas aeruginosa is the primary etiological agent in these patients. This study aimed to determine the prevalence of P. aeruginosa isolated from burn wound specimens and evaluate its antibiogram susceptibility patterns.
Methods: Swabs were collected from 424 patients with burns, between October 2023 and May 2024. Standard microbiological methods were employed for isolation, identification, and susceptibility testing of P. aeruginosa.
Results: The most frequent isolate was P. aeruginosa (168; 39.6%), followed by Klebsiella pneumoniae (115; 27.1%), and Staphylococcus aureus (82; 19.3%). The lowest isolation frequencies were recorded for Acinetobacter spp. and Proteus spp. (0.7% each). Significant statistical associations (P < 0.05) were found between antibiotic resistance and clinical procedures, such as surgical skin transplantation and debridement. P. aeruginosa isolates showed high resistance (90%) to third- and fourth-generation cephalosporins (cefepime, ceftazidime, and ticarcillin). Resistance to carbapenems was moderate (imipenem, 58%; meropenem, 62%), whereas colistin resistance remained exceptionally low (3%).
Conclusion: The isolation rates of P. aeruginosa from burn wound infections (BWI) were high in Sana’a. Resistance is strongly associated with length of hospital stay, surgical intervention, and prior antibiotic exposure
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