Anaphylaxis: A Case Report from Azal hospital, Sana'a, Yemen

Anaphylaxis is a severe life-threatening allergic reaction. This is a type I hypersensitivity reaction. Antibody-antigen reaction induces the release of inflammatory mediators. In this article, we report the case of a 55 years old female patient who presented with generalised urticaria, pruritus, skin edema, fever, abdominal pain, and dyspnea. Investigations showed only neutrophilia. The patient was immediately received intravenous (IV) chlorpheniramine 10 mg and intravenous hydrocortisone 100 mg with a slight response. The patient then received intravenous methylprednisolone 500 mg with dramatic improvement. This drug was administered once daily for three consecutive days.