Effectiveness of Butorphanol Intra Articular Injection in Signs and Symptoms of Internal Disorders of the Temporomandibular Joint Among Yemeni Patients in Sana'a City.

Abstract

Background and aim: TMJ arthralgia is a painful ailment that is thought to be related to local inflammation in the jaw joint. The purpose of the current study was to evaluate the effectiveness of a single intra-articular (IA) injection of butorphanol into the TMJ for lowering pain and improving mouth opening. The concept was that butorphanol would significantly lessen TMJ pain and improve mouth opening.

Methods: Eleven patients were treated in this serie, which was followed up on for three months. Participants in the study had to be at least 18 years old and have a unilateral TMJ arthralgia diagnosis. Butorphanol IA injections weighing 1 mL were given to all individuals. The main result was an analysis of the per protocol population's change in recorded pain intensity on a visual analogue scale (VAS) at maximum jaw opening.

Results: Mouth opening improved after treatment as values ​​increased: 1 week after treatment mean ± SD = 3.072 ± 0.373, after 1 month of treatment the values of mouth opening ​​increased significantly, the highest values ​​occurred after 3 months of treatment where the mouth-opening values ​​were twice the pre-treatment period.   Pre-treatment central trend measures of pain score were:  the mean ± SD =7.364 ± 1.12, the pain score decreased after treatment, one week after treatment the mean ± SD =3.636 ± 1.748, one month after treatment values decreased   significantly, the lowest pain scores occurred after 3 months of the treatment in which 25% of patients recorded 0 pain and 75% of patients recorded 1 or less pain score.

Conclusion: Following a single-dose IA injection, butorphanol was beneficial for lowering pain and improving mouth opening in individuals with TMJ arthralgia.